PyBOP (Benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate)
PyBOP is a high-efficiency phosphonium-based coupling reagent widely used for amide bond formation in peptide synthesis. It enables rapid coupling under mild conditions.
Applications
- Peptide synthesis (SPPS and solution-phase)
- Amide bond formation
- Medicinal chemistry
- Small-molecule synthesis
- Research and development laboratories
Chemical Information
CAS Number: 128625-52-5
Molecular Formula: C₁₈H₂₈F₆N₅OP
Molecular Weight: 520.4 g/mol
Appearance: White to off-white crystalline solids.
Handling & Storage
Store in a cool, dry place, tightly sealed, and protected from moisture. Handle using appropriate PPE. Refer to SDS for full safety and handling information.
Regulatory & Use Notice
For research and development use.
Not for human or veterinary use.